Published papers citing this grant

 

  1. Barfield R, Shen J, Just AC, Vokonas PS, Schwartz J, Baccarelli AA, VanderWeele TJ, Lin X. Testing for the indirect effect under the null for genome-wide mediation analyses. Genet Epidemiol. 2017 Dec;41(8):824-833. doi: 10.1002/gepi.22084. Epub 2017 Oct 29. PMID: 29082545; PMCID: PMC5696067
  2. Sun R, Carroll RJ, Christiani DC, Lin X. Testing for gene-environment interaction under exposure misspecification. Biometrics. 2018 Jun;74(2):653-662. doi: 10.1111/biom.12813. Epub 2017 Nov 9. PMID: 29120492; PMCID: PMC5943197.Chen LS, Hartz SM, Baker TB, Ma Y, L Saccone N, Bierut LJ. Use of polygenic risk scores of nicotine metabolism in predicting smoking behaviors. Pharmacogenomics. 2018 Dec;19(18):1383-1394. doi: 10.2217/pgs-2018-0081. Epub 2018 Nov 16. PMID: 30442082; PMCID: PMC6562697
  3. Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Consortium for Early Detection of Lung Cancer, Guida F, Sun N, Bantis LE, Muller DC, Li P, Taguchi A, Dhillon D, Kundnani DL, Patel NJ, Yan Q, Byrnes G, Moons KGM, Tjønneland A, Panico S, Agnoli C, Vineis P, Palli D, Bueno-de-Mesquita B, Peeters PH, Agudo A, Huerta JM, Dorronsoro M, Barranco MR, Ardanaz E, Travis RC, Byrne KS, Boeing H, Steffen A, Kaaks R, Hüsing A, Trichopoulou A, Lagiou P, La Vecchia C, Severi G, Boutron-Ruault MC, Sandanger TM, Weiderpass E, Nøst TH, Tsilidis K, Riboli E, Grankvist K, Johansson M, Goodman GE, Feng Z, Brennan P, Johansson M, Hanash SM. Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins. JAMA Oncol. 2018 Oct 1;4(10):e182078. doi: 10.1001/jamaoncol.2018.2078. Epub 2018 Oct 11. Erratum in: JAMA Oncol. 2018 Oct 1;4(10):1439. Erratum in: JAMA Oncol. 2019 Nov 14;: PMID: 30003238; PMCID: PMC6233784.
  4. Robbins HA, Katki HA, Cheung LC, Landy R, Berg CD. Insights for Management of Ground-Glass Opacities From the National Lung Screening Trial. J Thorac Oncol. 2019 Sep;14(9):1662-1665. doi: 10.1016/j.jtho.2019.05.012. Epub 2019 May 22. PMID: 31125735; PMCID: PMC6909540.
  5. McCaw ZR, Lane JM, Saxena R, Redline S, Lin X. Operating characteristics of the rank-based inverse normal transformation for quantitative trait analysis in genome-wide association studies. Biometrics. 2019 Dec 28. doi: 10.1111/biom.13214. Epub ahead of print. PMID: 31883270.
  6. Robbins HA, Johansson M. Defining Equity in Eligibility for Cancer Screening. JAMA Oncol. 2019 Nov 7:10.1001/jamaoncol.2019.4598. doi: 10.1001/jamaoncol.2019.4598. Epub ahead of print. PMID: 31697333; PMCID: PMC7202979.
  7. Landy R, Cheung LC, Berg CD, Chaturvedi AK, Robbins HA, Katki HA. Contemporary Implications of U.S. Preventive Services Task Force and Risk-Based Guidelines for Lung Cancer Screening Eligibility in the United States. Ann Intern Med. 2019 Sep 3;171(5):384-386. doi: 10.7326/M18-3617. Epub 2019 Jun 4. PMID: 31158854; PMCID: PMC6822170.
  8. Robbins HA, Katki HA, Cheung LC, Landy R, Berg CD. Insights for Management of Ground-Glass Opacities From the National Lung Screening Trial. J Thorac Oncol. 2019 Sep;14(9):1662-1665. doi: 10.1016/j.jtho.2019.05.012. Epub 2019 May 22. PMID: 31125735; PMCID: PMC6909540.
  9. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies, Chen H, Huffman JE, Brody JA, Wang C, Lee S, Li Z, Gogarten SM, Sofer T, Bielak LF, Bis JC, Blangero J, Bowler RP, Cade BE, Cho MH, Correa A, Curran JE, de Vries PS, Glahn DC, Guo X, Johnson AD, Kardia S, Kooperberg C, et al, Am J Hum Genet. 2019 Feb 7;104(2):260-274. doi:10.1016/j.ajhg.2018.12.012. Epub 2019 Jan 10. PMID: 30639324, PMCID: PMC6372261
  10. Liu Z, Lin X. A geometric perspective on the power of principal component association tests in multiple phenotype studies. J Am Stat Assoc. 2019;114(527):975-990. doi: 10.1080/01621459.2018.1513363. Epub 2019 Feb 26. PMID:31564761
  11. Ramsey AT, Prentice D, Ballard E, Chen LS, Bierut LJ. Leverage points to improve smoking cessation treatment in a large tertiary care hospital: a systems-based mixed methods study. BMJ Open. 2019 Jul 2;9(7):e030066. doi: 10.1136/bmjopen-2019-030066. PMID: 31270124; PMCID: PMC6609123.
  12. Robbins HA, Callister M, Sasieni P, Quaife SL, Cheung LC, Brennan P, Katki HA, Berg CD, Baldwin D, Johansson M. Benefits and harms in the National Lung Screening Trial: expected outcomes with a modern management protocol. Lancet Respir Med. 2019 Aug;7(8):655-656. doi: 10.1016/S2213-2600(19)30136-5. Epub 2019 May 7. Erratum in: Lancet Respir Med. 2019 Jul;7(7):e22. PMID: 31076382; PMCID: PMC6992839.
  13. Robbins HA, Katki HA, Cheung LC, Landy R, Berg CD. Insights for Management of Ground-Glass Opacities From the National Lung Screening Trial. J Thorac Oncol. 2019 Sep;14(9):1662-1665. doi: 10.1016/j.jtho.2019.05.012. Epub 2019 May 22. PMID: 31125735; PMCID: PMC6909540.
  14. Robbins HA, Berg CD, Cheung LC, Chaturvedi AK, Katki HA. Identification of Candidates for Longer Lung Cancer Screening Intervals Following a Negative Low-Dose Computed Tomography Result. J Natl Cancer Inst. 2019 Sep 1;111(9):996-999. doi: 10.1093/jnci/djz041. PMID: 30976808; PMCID: PMC6748798.
  15. Chen S, Lin X. Analysis in case-control sequencing association studies with different sequencing depths. Biostatistics. 2020 Jul 1;21(3):577-593. doi: 10.1093/biostatistics/kxy073. PMID: 30590456; PMCID: PMC7308042.
  16. Liu Y, Chen S, Li Z, Morrison AC, Boerwinkle E, Lin X. ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies. Am J Hum Genet. 2019 Mar 7;104(3):410-421. doi: 10.1016/j.ajhg.2019.01.002. PMID: 30849328; PMCID: PMC6407498.
  17. Is high vitamin B12 status a cause of lung cancer?, Fanidi A, Carreras-Torres R, Larose TL, Yuan JM, Stevens VL, Weinstein SJ,Albanes D, Prentice R, Pettinger M, Cai Q, Blot WJ, Arslan AA, Zeleniuch-Jacquotte A, McCullough ML, Le Marchand L, Wilkens LR, Haiman CA, Zhang X, Stampfer MJ, Smith-Warner SA, Giovannucci E, Giles GG, et al, Int J Cancer. 2018 Nov 29. doi:10.1002/ijc.32033. PMID: 30499135
  18. Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity, Ferreiro-Iglesias A, Lesseur C, McKay J, Hung RJ, Han Y, Zong X, Christiani D, Johansson M, Xiao X, Li Y, Qian DC, Ji X, Liu G, Caporaso N, Scelo G, Zaridze D, Mukeriya A, Kontic M, Ognjanovic S, Lissowska J, Szołkowska M, Swiatkowska B, et al, Nat Commun. 2018 Sep 25;9(1):3927. doi:10.1038/s41467-018-05890-2.PMID: 30254314, PMCID: PMC6156406
  19. Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk , Ji X, Bossé Y, Landi MT, Gui J, Xiao X, Qian D, Joubert P, Lamontagne M, Li Y,Gorlov I, de Biasi M, Han Y, Gorlova O, Hung RJ, Wu X, McKay J, Zong X,Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, et al, Nat Commun. 2018 Aug 13;9(1):3221. doi:10.1038/s41467-018-05074-y. PMID: 30104567, PMCID: PMC6089967
  20. Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers, Kachuri L, Saarela O, Bojesen SE, Davey Smith G, Liu G, Landi MT, Caporaso NE, Christiani DC, Johansson M, Panico S, Overvad K, Trichopoulou A, Vineis P, Scelo G, Zaridze D, Wu X, Albanes D, Diergaarde B, Lagiou P, Macfarlane GJ, Aldrich MC,Tardón A, et al, Int J Epidemiol. 2018Jul 28. doi: 10.1093/ije/dyy140. PubMed [citation] PMID: 30059977
  21. Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating ProteinsIntegrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Consortium for Early Detection of Lung Cancer., Guida F, Sun N, Bantis LE, Muller DC, Li P, Taguchi A, Dhillon D, Kundnani DL, Patel NJ, Yan Q, Byrnes G, Moons KGM,Tjønneland A, Panico S, Agnoli C, Vineis P, Palli D, Bueno-de-Mesquita B, Peeters PH, Agudo A, Huerta JM, et al, JAMA Oncol. 2018 Oct 1;4(10):e182078.doi: 10.1001/jamaoncol.2018.2078. Epub 2018 Oct 11. PMID:30003238, PMCID: PMC6233784
  22. Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer, Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, Pikielny CW, Neslund-Dudas C, Pinney SM, Anderson M, Kupert E, Bailey-Wilson J, Gaba C, et al, J Thorac Oncol. 2018 Oct;13(10):1483-1495. doi:10.1016/j.jtho.2018.06.016. Epub 2018 Jul 4. PMID: 29981437, PMCID: PMC6366341
  23. Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium minersRosenberger A, Hung RJ, Christiani DC, Caporaso NE, Liu G, Bojesen SE, Le Marchand L, Haiman CA, Albanes D, Aldrich MC, Tardon A, Fernández-Tardón G, Rennert G, Field JK, Kiemeney B, Lazarus P, Haugen A, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Brunnsstöm H, et al, Int Arch Occup Environ Health. 2018 Nov;91(8):937-950. doi: 10.1007/s00420-018-1334-3. Epub 2018 Jul 3. PMID: 29971594,PMCID: PMC6375683
  24. Genome-wide association study of familial lung cancer, Byun J, Schwartz AG, Lusk C, Wenzlaff AS, de Andrade M, Mandal D, Gaba C, Yang P, You M, Kupert EY, Anderson MW, Han Y, Li Y, Qian D, Stilp A, Laurie C, Nelson S, Zheng W, Hung RJ, Gaborieau V, Mckay J, Brennan P, et al, Carcinogenesis. 2018 Sep 21;39(9):1135-1140. doi: 10.1093/carcin/bgy080.PMID: 29924316, PMCID: PMC6148967
  25. Multi-Omics Analysis Reveals a HIF Network and Hub Gene EPAS1 Associated with Lung Adenocarcinoma, Wang Z, Wei Y, Zhang R, Su L, Gogarten SM, Liu G, Brennan P, Field JK, McKay JD, Lissowska J, Swiatkowska B, Janout V, Bolca C, Kontic M, Scelo G, Zaridze D, Laurie CC, Doheny KF, Pugh EK, Marosy BA, Hetrick KN, Xiao X, et al, EBioMedicine. 2018 Jun;32:93-101. doi:10.1016/j.ebiom.2018.05.024. Epub 2018 May 31. PMID: 29859855,PMCID: PMC6021270
  26. Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer, Feng Y, Wang Y, Liu H, Liu Z, Mills C, Owzar K, Xie J, Han Y, Qian DC, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Brüske I, Risch A, Ye Y, Wu X, et al, Mol Carcinog. 2018 Feb;57(2):216-224. doi: 10.1002/mc.22748. Epub 2017 Oct 31. PMID: 29071797, PMCID: PMC6128286
  27. Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population, Li Y, Xiao X, Han Y, Gorlova O, Qian D, Leighl N, Johansen JS, Barnett M, Chen C, Goodman G, Cox A, Taylor F, Woll P, Wichmann HE, Manz J, Muley T, Risch A, Rosenberger A, Arnold SM, Haura EB, Bolca C, Holcatova I, et al, Carcinogenesis. 2018 Mar 8;39(3):336-346. doi:10.1093/carcin/bgx113. PMID: 29059373, PMCID: PMC6248554
  28. A Decade of GWAS Results in Lung Cancer, Bossé Y, Amos CI, Cancer Epidemiol Biomarkers Prev. 2018 Apr;27(4):363-379. doi: 10.1158/1055-9965.EPI-16-0794. Epub 2017 Jun 14. PMID: 28615365, PMCID: PMC6464125
  29. S01.07 The U19 Plans for Integration of Biomarkers Into Future Lung Cancer Screening, C. Amos, R.J. Hung On Behalf of The International Lung Cancer Consortium, P. Brennan, Journal of Thoracic Oncology, Volume 14, Issue 10, S197 - S198
  30. MS18. 03 Amolecular Diagnostics, Incorporating GWAS and Risk Models: Future Approaches to the Identification of High-Risk Individuals, P. Brennan, C. Amos, Journal of Thoracic Oncology, Volume 14, Issue 10, S193
  31. Appraising the causal relevance of DNA methylation for risk of lung cancer. Battram T, Richmond RC, Baglietto L, Haycock PC, Perduca V, Bojesen SE, Gaunt TR, Hemani G, Guida F, Carreras-Torres R, Hung R, Amos CI, Freeman JR, Sandanger TM, Nøst TH, Nordestgaard BG, Teschendorff AE, Polidoro S, Vineis P, Severi G, Hodge AM, Giles GG, Grankvist K, Johansson MB, Johansson M, Davey Smith G, Relton CL. Int J Epidemiol. 2019 Oct 1;48(5):1493-1504. doi: 10.1093/ije/dyz190. PMID: 31549173 Free PMC article
  32. Jiang X, Finucane HK, Schumacher FR, Schmit SL, Tyrer JP, Han Y, Michailidou K, Lesseur C, Kuchenbaecker KB, Dennis J, Conti DV, Casey G, Gaudet MM, Huyghe JR, Albanes D, Aldrich MC, Andrew AS, Andrulis IL, Anton-Culver H, Antoniou AC, Antonenkova NN, Arnold SM, Aronson KJ, Arun BK, Bandera EV, Barkardottir RB, Barnes DR, Batra J, Beckmann MW, Benitez J, Benlloch S, Berchuck A, Berndt SI, Bickeboller H, Bien SA, Blomqvist C, Boccia S, Bogdanova NV, Bojesen SE, Bolla MK, Brauch H, Brenner H, Brenton JD, Brook MN, Brunet J, Brunnstrom H, Buchanan DD, Burwinkel B, Butzow R, Cadoni G, Caldes T, Caligo MA, Campbell I, Campbell PT, Cancel-Tassin G, Cannon-Albright L, Campa D, Caporaso N, Carvalho AL, Chan AT, Chang-Claude J, Chanock SJ, Chen C, Christiani DC, Claes KBM, Claessens F, Clements J, Collee JM, Correa MC, Couch FJ, Cox A, Cunningham JM, Cybulski C, Czene K, Daly MB, deFazio A, Devilee P, Diez O, Gago-Dominguez M, Donovan JL, Dork T, Duell EJ, Dunning AM, Dwek M, Eccles DM, Edlund CK, Edwards DRV, Ellberg C, Evans DG, Fasching PA, Ferris RL, Liloglou T, Figueiredo JC, Fletcher O, Fortner RT, Fostira F, Franceschi S, Friedman E, Gallinger SJ, Ganz PA, Garber J, Garcia-Saenz JA, Gayther SA, Giles GG, Godwin AK, Goldberg MS, Goldgar DE, Goode EL, Goodman MT, Goodman G, Grankvist K, Greene MH, Gronberg H, Gronwald J, Guenel P, Hakansson N, Hall P, Hamann U, Hamdy FC, Hamilton RJ, Hampe J, Haugen A, Heitz F, Herrero R, Hillemanns P, Hoffmeister M, Hogdall E, Hong YC, Hopper JL, Houlston R, Hulick PJ, Hunter DJ, Huntsman DG, Idos G, Imyanitov EN, Ingles SA, Isaacs C, Jakubowska A, James P, Jenkins MA, Johansson M, Johansson M, John EM, Joshi AD, Kaneva R, Karlan BY, Kelemen LE, Kuhl T, Khaw KT, Khusnutdinova E, Kibel AS, Kiemeney LA, Kim J, Kjaer SK, Knight JA, Kogevinas M, Kote-Jarai Z, Koutros S, Kristensen VN, Kupryjanczyk J, Lacko M, Lam S, Lambrechts D, Landi MT, Lazarus P, Le ND, Lee E, Lejbkowicz F, Lenz HJ, Leslie G, Lessel D, Lester J, Levine DA, Li L, Li CI, Lindblom A, Lindor NM, Liu G, Loupakis F, Lubinski J, Maehle L, Maier C, Mannermaa A, Marchand LL, Margolin S, May T, McGuffog L, Meindl A, Middha P, Miller A, Milne RL, MacInnis RJ, Modugno F, Montagna M, Moreno V, Moysich KB, Mucci L, Muir K, Mulligan AM, Nathanson KL, Neal DE, Ness AR, Neuhausen SL, Nevanlinna H, Newcomb PA, Newcomb LF, Nielsen FC, Nikitina-Zake L, Nordestgaard BG, Nussbaum RL, Offit K, Olah E, Olama AAA, Olopade OI, Olshan AF, Olsson H, Osorio A, Pandha H, Park JY, Pashayan N, Parsons MT, Pejovic T, Penney KL, Peters WHM, Phelan CM, Phipps AI, Plaseska-Karanfilska D, Pring M, Prokofyeva D, Radice P, Stefansson K, Ramus SJ, Raskin L, Rennert G, Rennert HS, van Rensburg EJ, Riggan MJ, Risch HA, Risch A, Roobol MJ, Rosenstein BS, Rossing MA, De Ruyck K, Saloustros E, Sandler DP, Sawyer EJ, Schabath MB, Schleutker J, Schmidt MK, Setiawan VW, Shen H, Siegel EM, Sieh W, Singer CF, Slattery ML, Sorensen KD, Southey MC, Spurdle AB, Stanford JL, Stevens VL, Stintzing S, Stone J, Sundfeldt K, Sutphen R, Swerdlow AJ, Tajara EH, Tangen CM, Tardon A, Taylor JA, Teare MD, Teixeira MR, Terry MB, Terry KL, Thibodeau SN, Thomassen M, Bjorge L, Tischkowitz M, Toland AE, Torres D, Townsend PA, Travis RC, Tung N, Tworoger SS, Ulrich CM, Usmani N, Vachon CM, Van Nieuwenhuysen E, Vega A, Aguado-Barrera ME, Wang Q, Webb PM, Weinberg CR, Weinstein S, Weissler MC, Weitzel JN, West CML, White E, Whittemore AS, Wichmann HE, Wiklund F, Winqvist R, Wolk A, Woll P, Woods M, Wu AH, Wu X, Yannoukakos D, Zheng W, Zienolddiny S, Ziogas A, Zorn KK, Lane JM, Saxena R, Thomas D, Hung RJ, Diergaarde B, McKay J, Peters U, Hsu L, Garcia-Closas M, Eeles RA, Chenevix-Trench G, Brennan PJ, Haiman CA, Simard J, Easton DF, Gruber SB, Pharoah PDP, Price AL, Pasaniuc B, Amos CI, Kraft P, Lindstrom S. Shared heritability and functional enrichment across six solid cancers. Nature communications 2019; 10: 431.
  33. Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK, Ying J, Li Y, Han Y, Ji X, Chen W, Wu X, Gorlov IP, Na J, de Andrade M, Liu G, Brhane Y, Diao N, Wenzlaff A, Davies MPA, Liloglou T, Timofeeva M, Muley T, Rennert H, Saliba W, Ryan BM, Bowman E, Barros-Dios JM, Perez-Rios M, Morgenstern H, Zienolddiny S, Skaug V, Ugolini D, Bonassi S, van der Heijden E, Tardon A, Bojesen SE, Landi MT, Johansson M, Bickeboller H, Arnold S, Le Marchand L, Melander O, Andrew A, Grankvist K, Caporaso N, Teare MD, Schabath MB, Aldrich MC, Kiemeney LA, Wichmann HE, Lazarus P, Mayordomo J, Neri M, Haugen A, Zhang ZF, Ruano-Ravina A, Brenner H, Harris CC, Orlow I, Rennert G, Risch A, Brennan P, Christiani DC, Amos CI, Yang P, Gorlova OY. Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2019.
  34. Gorlov IP, Gorlova OY, Amos CI. Untouchable genes in the human genome: Identifying ideal targets for cancer treatment. Cancer Genet 2019; 231-232: 67-79.
  35. Liu Z, Lin X. A Geometric Perspective on the Power of Principal Component Association Tests in Multiple Phenotype Studies. J Am Stat Assoc 2019; 114: 975-990.
  36. Ramsey AT, Proctor EK, Chambers DA, Garbutt JM, Malone S, Powderly WG, Bierut LJ. Designing for Accelerated Translation (DART) of Emerging Innovations in Health. J Clin Transl Sci 2019; 3: 53-58.
  37. Tozzi V, Rosenberger A, Kube D, Bickeboller H. Global, pathway and gene coverage of three Illumina arrays with respect to inflammatory and immune-related pathways. European journal of human genetics : EJHG 2019; 27: 1716-1723
  38. Thomas CE, Wang R, Adams-Haduch J, Murphy SE, Ueland PM, Midttun Ø, Brennan P, Johansson M, Gao YT, Yuan JM. Urinary Cotinine Is as Good a Biomarker as Serum Cotinine for Cigarette Smoking Exposure and Lung Cancer Risk Prediction. Cancer Epidemiol Biomarkers Prev. 2020 Jan;29(1):127-132. doi: 10.1158/1055-9965.EPI-19-0653. Epub 2019 Nov 4.
  39. Xu M, Yao Y, Chen H, Zhang S, Cao SM, Zhang Z, Luo B, Liu Z, Li Z, Xiang T, He G, Feng QS, Chen LZ, Guo X, Jia WH, Chen MY, Zhang X, Xie SH, Peng R, Chang ET, Pedergnana V, Feng L, Bei JX, Xu RH, Zeng MS, Ye W, Adami HO, Lin X, Zhai W, Zeng YX, Liu J. Genome sequencing analysis identifies Epstein-Barr virus subtypes associated with high risk of nasopharyngeal carcinoma. Nature genetics 2019; 51: 1131-1136.
  40. Li Z, Li X, Liu Y, Shen J, Chen H, Zhou H, Morrison AC, Boerwinkle E, Lin X. Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies. Am J Hum Genet 2019; 104: 802-814.
  41. Chen H, Huffman JE, Brody JA, Wang C, Lee S, Li Z, Gogarten SM, Sofer T, Bielak LF, Bis JC, Blangero J, Bowler RP, Cade BE, Cho MH, Correa A, Curran JE, de Vries PS, Glahn DC, Guo X, Johnson AD, Kardia S, Kooperberg C, Lewis JP, Liu X, Mathias RA, Mitchell BD, O'Connell JR, Peyser PA, Post WS, Reiner AP, Rich SS, Rotter JI, Silverman EK, Smith JA, Vasan RS, Wilson JG, Yanek LR, Redline S, Smith NL, Boerwinkle E, Borecki IB, Cupples LA, Laurie CC, Morrison AC, Rice KM, Lin X. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies. Am J Hum Genet 2019; 104: 260-274
  42. Kachuri L, Johansson M, Rashkin SR, Graff RE, Bosse Y, Manem V, Caporaso NE, Landi MT, Christiani DC, Vineis P, Liu G, Scelo G, Zaridze D, Shete SS, Albanes D, Aldrich MC, Tardon A, Rennert G, Chen C, Goodman GE, Doherty JA, Bickeboller H, Field JK, Davies MP, Dawn Teare M, Kiemeney LA, Bojesen SE, Haugen A, Zienolddiny S, Lam S, Le Marchand L, Cheng I, Schabath MB, Duell EJ, Andrew AS, Manjer J, Lazarus P, Arnold S, McKay JD, Emami NC, Warkentin MT, Brhane Y, Obeidat M, Martin RM, Relton C, Davey Smith G, Haycock PC, Amos CI, Brennan P, Witte JS, Hung RJ. Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. Nature communications 2020; 11: 27.
  43. Bosse Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeboller H, Bojesen SE, Brennan P, Brunnstrom H, Caporaso N, Chen C, Christiani DC, Field JK, Goodman G, Grankvist K, Houlston R, Johansson M, Johansson M, Kiemeney LA, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Rennert G, Risch A, Rosenberg SM, Schabath MB, Shete S, Song Z, Stevens VL, Tardon A, Wichmann HE, Woll P, Zienolddiny S, Obeidat M, Timens W, Hung RJ, Joubert P, Amos CI, McKay JD. Transcriptome-wide association study reveals candidate causal genes for lung cancer. International journal of cancer Journal international du cancer 2020; 146: 1862-1878.
  44. Shin SJ, Dodd-Eaton EB, Peng G, Bojadzieva J, Chen J, Amos CI, Frone MN, Khincha PP, Mai PL, Savage SA, Ballinger ML, Thomas DM, Yuan Y, Strong LC, Wang W. Penetrance of Different Cancer Types in Families with Li-Fraumeni Syndrome: A Validation Study Using Multicenter Cohorts. Cancer Res 2020; 80: 354-360.
  45. Shin SJ, Dodd-Eaton EB, Gao F, Bojadzieva J, Chen J, Kong X, Amos CI, Ning J, Strong LC, Wang W. Penetrance Estimates Over Time to First and Second Primary Cancer Diagnosis in Families with Li-Fraumeni Syndrome: A Single Institution Perspective. Cancer Res 2020; 80: 347-353.
  46. Bossé Y, Li Z, Xia J, Manem V, Carreras-Torres R, Gabriel A, Gaudreault N, Albanes D, Aldrich MC, Andrew A, Arnold S, Bickeböller H, Bojesen SE, Brennan P, Brunnstrom H, Caporaso N, Chen C, Christiani DC, Field JK, Goodman G, Grankvist K, Houlston R, Johansson M, Johansson M, Kiemeney LA, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Rennert G, Risch A, Rosenberg SM, Schabath MB, Shete S, Song Z, Stevens VL, Tardon A, Wichmann HE, Woll P, Zienolddiny S, Obeidat M, Timens W, Hung RJ, Joubert P, Amos CI, McKay JD. Transcriptome-wide association study reveals candidate causal genes for lung cancer. International journal of cancer Journal international du cancer 2020; 146: 1862-1878
  47. Ji X, Mukherjee S, Landi MT, Bosse Y, Joubert P, Zhu D, Gorlov I, Xiao X, Han Y, Gorlova O, Hung RJ, Brhane Y, Carreras-Torres R, Christiani DC, Caporaso N, Johansson M, Liu G, Bojesen SE, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Chen C, Byun J, Dragnev KH, Field JK, Kiemeney LF, Lazarus P, Zienolddiny S, Lam S, Schabath MB, Andrew AS, Bertazzi PA, Pesatori AC, Diao N, Su L, Song L, Zhang R, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman C, Wilkens L, Fernandez-Somoano A, Fernandez-Tardon G, Heijden EHFMV, Kim JH, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Goodman GE, Cox A, Taylor F, Woll P, Wichmann E, Muley T, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd F, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Butler LM, Offit K, Srinivasan P, Bandlamudi C, Hellmann MD, Solit DB, Robson ME, Rudin CM, Stadler ZK, Taylor BS, Berger MF, Houlston R, McLaughlin J, Stevens V, Nickle DC, Obeidat M, Timens W, Artigas MS, Shete S, Brenner H, Chanock S, Brennan P, McKay JD, Amos CI. Protein-altering germline mutations implicate novel genes related to lung cancer development. Nat Commun. 2020 May 11;11(1):2220. doi: 10.1038/s41467-020-15905-6. PMID: 32393777
  48. Cai G, Bossé Y, Xiao F, Kheradmand F, Amos CI. Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2. Am J Respir Crit Care Med 2020; 201: 1557-1559.
  49. Dai J, Huang M, Amos CI, Hung RJ, Tardon A, Andrew A, Chen C, Christiani DC, Albanes D, Rennert G, Fan J, Goodman G, Liu G, Field JK, Grankvist K, Kiemeney LA, Le Marchand L, Schabath MB, Johansson M, Aldrich MC, Johansson M, Caporaso N, Lazarus P, Lam S, Bojesen SE, Arnold S, Landi MT, Risch A, Wichmann HE, Bickeboller H, Brennan P, Shete S, Melander O, Brunnstrom H, Zienolddiny S, Woll P, Stevens V, Hu Z, Shen H. Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk. International journal of cancer Journal international du cancer 2020; 146: 2855-2864.
  50. Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeboller H, Bojesen SE, Brennan P, Brunnstrom H, Melander O, Caporaso NE, Landi MT, Chen C, Goodman GE, Christiani DC, Cox A, Field JK, Johansson M, Kiemeney LA, Lam S, Lazarus P, Le Marchand L, Rennert G, Risch A, Schabath MB, Shete SS, Tardon A, Zienolddiny S, Shen H, Amos CI. Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization. International journal of cancer Journal international du cancer 2020.
  51. Sun R, Lin X. Genetic Variant Set-Based Tests Using the Generalized Berk-Jones Statistic with Application to a Genome-Wide Association Study of Breast Cancer. J Am Stat Assoc 2020; 115: 1079-1091.
  52. Zheng X, Amos CI, Frost HR. Cancer prognosis prediction using somatic point mutation and copy number variatibraon data: a comparison of gene-level and pathway-based models. BMC bioinformatics 2020; 21: 467.
  53. Brhane Y, Yang P, Christiani DC, Liu G, McLaughlin JR, Brennan P, Shete S, Field JK, Tardón A, Kohno T, Shiraishi K, Matsuo K, Bossé Y, Amos CI, Hung RJ. Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020; 29: 1983-1992.
  54. Larose TL, Meheus F, Brennan P, Johansson M, Robbins HA. Assessment of Biomarker Testing for Lung Cancer Screening Eligibility. JAMA network open 2020; 3: e200409.
  55. Callister MEJ, Sasieni P, Robbins HA. Overdiagnosis in lung cancer screening. Lancet Respir Med. 2021 Jan;9(1):7-9. doi: 10.1016/S2213-2600(20)30553-1. PMID: 33412118.
  56. Luyapan J, Ji X, Li S, Xiao X, Zhu D, Duell EJ, Christiani DC, Schabath MB, Arnold SM, Zienolddiny S, Brunnström H, Melander O, Thornquist MD, MacKenzie TA, Amos CI, Gui J. A new efficient method to detect genetic interactions for lung cancer GWAS. BMC Med Genomics. 2020 Oct 30;13(1):162. doi: 10.1186/s12920-020-00807-9. PMID: 33126877; PMCID: PMC7596958.
  57. Zheng X, Amos CI, Frost HR. Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models. BMC Bioinformatics. 2020 Oct 20;21(1):467. doi: 10.1186/s12859-020-03791-0. PMID: 33081688; PMCID: PMC7574407.
  58. Zhou W, Liu G, Hung RJ, Haycock PC, Aldrich MC, Andrew AS, Arnold SM, Bickeböller H, Bojesen SE, Brennan P, Brunnström H, Melander O, Caporaso NE, Landi MT, Chen C, Goodman GE, Christiani DC, Cox A, Field JK, Johansson M, Kiemeney LA, Lam S, Lazarus P, Le Marchand L, Rennert G, Risch A, Schabath MB, Shete SS, Tardón A, Zienolddiny S, Shen H, Amos CI. Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization. Int J Cancer. 2021 Mar 1;148(5):1077-1086. doi: 10.1002/ijc.33292. Epub 2020 Sep 23. PMID: 32914876; PMCID: PMC7845289.
  59. Sun R, Xu M, Li X, Gaynor S, Zhou H, Li Z, Bossé Y, Lam S, Tsao MS, Tardon A, Chen C, Doherty J, Goodman G, Bojesen SE, Landi MT, Johansson M, Field JK, Bickeböller H, Wichmann HE, Risch A, Rennert G, Arnold S, Wu X, Melander O, Brunnström H, Le Marchand L, Liu G, Andrew A, Duell E, Kiemeney LA, Shen H, Haugen A, Johansson M, Grankvist K, Caporaso N, Woll P, Dawn Teare M, Scelo G, Hong YC, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Albanes D, Mak R, Barbie D, Brennan P, Hung RJ, Amos CI, Christiani DC, Lin X. Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer. Genet Epidemiol. 2021 Feb;45(1):99-114. doi: 10.1002/gepi.22358. Epub 2020 Sep 14. PMID: 32924180; PMCID: PMC7855632.
  60. Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, Sun R, Dey R, Arnett DK, Aslibekyan S, Ballantyne CM, Bielak LF, Blangero J, Boerwinkle E, Bowden DW, Broome JG, Conomos MP, Correa A, Cupples LA, Curran JE, Freedman BI, Guo X, Hindy G, Irvin MR, Kardia SLR, Kathiresan S, Khan AT, Kooperberg CL, Laurie CC, Liu XS, Mahaney MC, Manichaikul AW, Martin LW, Mathias RA, McGarvey ST, Mitchell BD, Montasser ME, Moore JE, Morrison AC, O'Connell JR, Palmer ND, Pampana A, Peralta JM, Peyser PA, Psaty BM, Redline S, Rice KM, Rich SS, Smith JA, Tiwari HK, Tsai MY, Vasan RS, Wang FF, Weeks DE, Weng Z, Wilson JG, Yanek LR; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Lipids Working Group, Neale BM, Sunyaev SR, Abecasis GR, Rotter JI, Willer CJ, Peloso GM, Natarajan P, Lin X. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet. 2020 Sep;52(9):969-983. doi: 10.1038/s41588-020-0676-4. Epub 2020 Aug 24. PMID: 32839606; PMCID: PMC7483769.
  61. Gorlov IP, Amos CI, Tsavachidis S, Begg C, Hernando E, Cheng C, Shen R, Orlow I, Luo L, Ernstoff MS, Parker J, Thomas NE, Gorlova OY, Berwick M. Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma. Hum Mutat. 2020 Jul 9:10.1002/humu.24078. doi: 10.1002/humu.24078. Epub ahead of print. PMID: 32643855; PMCID: PMC7794094.
  62. Cai G, Bossé Y, Xiao F, Kheradmand F, Amos CI. Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2. Am J Respir Crit Care Med. 2020 Jun 15;201(12):1557-1559. doi: 10.1164/rccm.202003-0693LE. PMID: 32329629; PMCID: PMC7301735.
  63. Ostrin EJ, Sidransky D, Spira A, Hanash SM. Biomarkers for Lung Cancer Screening and Detection. Cancer Epidemiol Biomarkers Prev. 2020 Dec;29(12):2411-2415. doi: 10.1158/1055-9965.EPI-20-0865. Epub 2020 Oct 22.
  64. Hung RJ, Warkentin MT, Brhane Y, Chatterjee N, Christiani DC, Landi MT, Caporaso NE, Liu G, Johansson M, Albanes D, Le Marchand L, Tardon A, Rennert G, Bojesen SE, Chen C, Field JK, Kiemeney LA, Lazarus P, Zienolddiny S, Lam S, Andrew AS, Arnold SM, et al. Assessing Lung Cancer Absolute Risk Trajectory based on a Polygenic Risk Model. Cancer Res. 2021 Jan 20. pii: canres.1237.2020. doi: 10.1158/0008-5472.CAN-20-1237.
  65. Chen H, Huffman JE, Brody JA, Wang C, Lee S, Li Z, Gogarten SM, Sofer T, Bielak LF, Bis JC, Blangero J, Bowler RP, Cade BE, Cho MH, Correa A, Curran JE, de Vries PS, Glahn DC, Guo X, Johnson AD, Kardia S, Kooperberg C, Lewis JP, Liu X, Mathias RA, Mitchell BD, O'Connell JR, Peyser PA, Post WS, Reiner AP, Rich SS, Rotter JI, Silverman EK, Smith JA, Vasan RS, Wilson JG, Yanek LR, Redline S, Smith NL, Boerwinkle E, Borecki IB, Cupples LA, Laurie CC, Morrison AC, Rice KM, Lin X. Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies. Am J Hum Genet 2019; 104: 260-274.
  66. Oluyomi AO, Gunter SM, Leining LM, Murray KO, Amos C. COVID-19 Community Incidence and Associated Neighborhood-Level Characteristics in Houston, Texas, USA. Int J Environ Res Public Health. 2021;18(4). Epub 2021/02/10. doi: 10.3390/ijerph18041495. PubMed PMID: 33557439; PMCID: PMC7915818.
  67. Naseri A, Shi J, Lin X, Zhang S, Zhi D. RAFFI: Accurate and fast familial relationship inference in large scale biobank studies using RaPID. PLoS genetics. 2021;17(1):e1009315. Epub 2021/01/22. doi: 10.1371/journal.pgen.1009315. PubMed PMID: 33476339; PMCID: PMC7853505.
  68. Baldwin DR, Callister ME, Crosbie PA, O'Dowd EL, Rintoul RC, Robbins HA, Steele RJC. Biomarkers in lung cancer screening: the importance of study design. Eur Respir J. 2021;57(1). Epub 2021/01/16. doi: 10.1183/13993003.04367-2020. PubMed PMID: 33446580.
  69. Callister MEJ, Sasieni P, Robbins HA. Overdiagnosis in lung cancer screening. Lancet Respir Med. 2021;9(1):7-9. Epub 2021/01/08. doi: 10.1016/S2213-2600(20)30553-1. PubMed PMID: 33412118.
  70. Landy R, Young CD, Skarzynski M, Cheung LC, Berg CD, Rivera MP, Robbins HA, Chaturvedi AK, Katki HA. Using Prediction-Models to Reduce Persistent Racial/Ethnic Disparities in Draft 2020 USPSTF Lung-Cancer Screening Guidelines. Journal of the National Cancer Institute. 2021. Epub 2021/01/06. doi: 10.1093/jnci/djaa211. PubMed PMID: 33399825.
  71. Lesseur C, Ferreiro-Iglesias A, McKay JD, Bosse Y, Johansson M, Gaborieau V, Landi MT, Christiani DC, Caporaso NC, Bojesen SE, Amos CI, Shete S, Liu G, Rennert G, Albanes D, Aldrich MC, Tardon A, Chen C, Triantafillos L, Field JK, Teare MD, Kiemeney LA, Diergaarde B, Ferris RL, Zienolddiny S, Lam S, Olshan AF, Weissler MC, Lacko M, Risch A, Bickeboller H, Ness AR, Thomas S, Le Marchand L, Schabath MB, Wunsch-Filho V, Tajara EH, Andrew AS, Clifford GM, Lazarus P, Grankvist K, Johansson M, Arnold S, Melander O, Brunnstrom H, Boccia S, Cadoni G, Timens W, Obeidat M, Xiao X, Houlston RS, Hung RJ, Brennan P. Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers. PLoS genetics. 2021;17(3):e1009254. Epub 2021/03/06. doi: 10.1371/journal.pgen.1009254. PubMed PMID: 33667223.