Integrative Analysis of Lung Cancer Etiology and Risk

Publications Citing this Grant

• Baldwin, D. R., M. E. Callister, P. A. Crosbie, E. L. O'Dowd, R. C. Rintoul, H. A. Robbins, and R. J. C. Steele. "Biomarkers in Lung Cancer Screening: The Importance of Study Design." Eur Respir J 57, no. 1 (Jan 2021).
• Barfield, R., J. Shen, A. C. Just, P. S. Vokonas, J. Schwartz, A. A. Baccarelli, T. J. VanderWeele, and X. Lin. "Testing for the Indirect Effect under the Null for Genome-Wide Mediation Analyses." Genet Epidemiol 41, no. 8 (Dec 2017): 824-33.
• Battram, T., R. C. Richmond, L. Baglietto, P. C. Haycock, V. Perduca, S. E. Bojesen, T. R. Gaunt, et al. "Appraising the Causal Relevance of DNA Methylation for Risk of Lung Cancer." Int J Epidemiol 48, no. 5 (Oct 1 2019): 1493-504.
• Bierut, L. J. "Using Genomic Profiing for Understanding and Improving Response to Smoking Cessation Treatement." Current Epidemiology Reports 6, no. 4 (2019): 486-90.
• Bosse, Y., and C. I. Amos. "A Decade of Gwas Results in Lung Cancer." Cancer Epidemiol Biomarkers Prev 27, no. 4 (Apr 2018): 363-79.
• Bosse, Y., Z. Li, J. Xia, V. Manem, R. Carreras-Torres, A. Gabriel, N. Gaudreault, et al. "Transcriptome-Wide Association Study Reveals Candidate Causal Genes for Lung Cancer." Int J Cancer 146, no. 7 (Apr 1 2020): 1862-78.
• Brhane, Y., P. Yang, D. C. Christiani, G. Liu, J. R. McLaughlin, P. Brennan, S. Shete, et al. "Genetic Determinants of Lung Cancer Prognosis in Never Smokers: A Pooled Analysis in the International Lung Cancer Consortium." Cancer Epidemiol Biomarkers Prev 29, no. 10 (Oct 2020): 1983-92.
• Byun, J., Y. Han, Q. T. Ostrom, J. Edelson, K. M. Walsh, R. W. Pettit, M. L. Bondy, et al. "The Shared Genetic Architectures between Lung Cancer and Multiple Polygenic Phenotypes in Genome-Wide Association Studies." Cancer Epidemiol Biomarkers Prev 30, no. 6 (Jun 2021): 1156-64.
• Byun, J., A. G. Schwartz, C. Lusk, A. S. Wenzlaff, M. de Andrade, D. Mandal, C. Gaba, et al. "Genome-Wide Association Study of Familial Lung Cancer." Carcinogenesis 39, no. 9 (Sep 21 2018): 1135-40.
• Cai, G., Y. Bosse, F. Xiao, F. Kheradmand, and C. I. Amos. "Tobacco Smoking Increases the Lung Gene Expression of Ace2, the Receptor of Sars-Cov-2." Am J Respir Crit Care Med 201, no. 12 (Jun 15 2020): 1557-59.
• Callister, M. E. J., P. Sasieni, and H. A. Robbins. "Overdiagnosis in Lung Cancer Screening." Lancet Respir Med 9, no. 1 (Jan 2021): 7-9.
• Chen, H., J. E. Huffman, J. A. Brody, C. Wang, S. Lee, Z. Li, S. M. Gogarten, et al. "Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies." Am J Hum Genet 104, no. 2 (Feb 7 2019): 260-74.
• Chen, H., A. Majumdar, L. Wang, S. Kar, K. M. Brown, H. Feng, C. Turman, et al. "Large-Scale Cross-Cancer Fine-Mapping of the 5p15.33 Region Reveals Multiple Independent Signals." HGG Adv 2, no. 3 (Jul 8 2021): 100041.
• Chen, L. S., T. B. Baker, J. P. Miller, M. Bray, N. Smock, J. Chen, F. Stoneking, et al. "Genetic Variant in Chrna5 and Response to Varenicline and Combination Nicotine Replacement in a Randomized Placebo-Controlled Trial." Clin Pharmacol Ther 108, no. 6 (Dec 2020): 1315-25.
• Chen, L. S., S. M. Hartz, T. B. Baker, Y. Ma, L. Saccone N, and L. J. Bierut. "Use of Polygenic Risk Scores of Nicotine Metabolism in Predicting Smoking Behaviors." Pharmacogenomics 19, no. 18 (Dec 2018): 1383-94.
• Chen, S., and X. Lin. "Analysis in Case-Control Sequencing Association Studies with Different Sequencing Depths." Biostatistics 21, no. 3 (Jul 1 2020): 577-93.
• Chen, X., K. G. Muhammad, C. Madeeha, W. Fu, L. Xu, Y. Hu, J. Liu, et al. "Calculated Indices of Volatile Organic Compounds (Vocs) in Exhalation for Lung Cancer Screening and Early Detection." Lung Cancer 154 (Apr 2021): 197-205.
• Dai, J., Z. Li, C. I. Amos, R. J. Hung, A. Tardon, A. S. Andrew, C. Chen, et al. "Systematic Analyses of Regulatory Variants in Dnase I Hypersensitive Sites Identified Two Novel Lung Cancer Susceptibility Loci." Carcinogenesis 40, no. 3 (May 14 2019): 432-40.
• Fanidi, A., R. Carreras-Torres, T. L. Larose, J. M. Yuan, V. L. Stevens, S. J. Weinstein, D. Albanes, et al. "Is High Vitamin B12 Status a Cause of Lung Cancer?". Int J Cancer 145, no. 6 (Sep 15 2019): 1499-503.
• Feng, Y., Y. Wang, H. Liu, Z. Liu, C. Mills, K. Owzar, J. Xie, et al. "Novel Genetic Variants in the P38mapk Pathway Gene Zak and Susceptibility to Lung Cancer." Mol Carcinog 57, no. 2 (Feb 2018): 216-24.
• Ferreiro-Iglesias, A., C. Lesseur, J. McKay, R. J. Hung, Y. Han, X. Zong, D. Christiani, et al. "Fine Mapping of Mhc Region in Lung Cancer Highlights Independent Susceptibility Loci by Ethnicity." Nat Commun 9, no. 1 (Sep 25 2018): 3927.
• Gauderman, W. J., B. Mukherjee, H. Aschard, L. Hsu, J. P. Lewinger, C. J. Patel, J. S. Witte, et al. "Update on the State of the Science for Analytical Methods for Gene-Environment Interactions." Am J Epidemiol 186, no. 7 (Oct 1 2017): 762-70.
• Gorlov, I. P., O. Y. Gorlova, and C. I. Amos. "Untouchable Genes in the Human Genome: Identifying Ideal Targets for Cancer Treatment." Cancer Genet 231-232 (Feb 2019): 67-79.
• Gorlova, O. Y., X. Xiao, S. Tsavachidis, C. I. Amos, and I. P. Gorlov. "Snp Characteristics and Validation Success in Genome Wide Association Studies." Hum Genet 141, no. 2 (Feb 2022): 229-38.
• Hancock, D. B., Y. Guo, G. W. Reginsson, N. C. Gaddis, S. M. Lutz, R. Sherva, A. Loukola, et al. "Genome-Wide Association Study across European and African American Ancestries Identifies a Snp in Dnmt3b Contributing to Nicotine Dependence." Mol Psychiatry 23, no. 9 (Sep 2018): 1911-19.
• Ho, J. T. K., R. F. Tyndale, T. B. Baker, C. I. Amos, A. Chiu, N. Smock, J. Chen, L. J. Bierut, and L. S. Chen. "Racial Disparities in Intensity of Smoke Exposure and Nicotine Intake among Low-Dependence Smokers." Drug Alcohol Depend 221 (Apr 1 2021): 108641.
• Hong, W., A. Li, Y. Liu, X. Xiao, D. C. Christiani, R. J. Hung, J. McKay, et al. "Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors." Cancer Res 82, no. 2 (Jan 15 2022): 199-209.
• Hung, R. J. "Biomarker-Based Lung Cancer Screening Eligibility: Implementation Considerations." Cancer Epidemiol Biomarkers Prev 31, no. 4 (Apr 1 2022): 698-701.
• Hung, R. J., M. R. Spitz, R. S. Houlston, A. G. Schwartz, J. K. Field, J. Ying, Y. Li, et al. "Lung Cancer Risk in Never-Smokers of European Descent Is Associated with Genetic Variation in the 5p15.33 Tert-Clptm1ll Region." J Thorac Oncol 14, no. 8 (Aug 2019): 1360-69.
• Hung, R. J., M. T. Warkentin, Y. Brhane, N. Chatterjee, D. C. Christiani, M. T. Landi, N. E. Caporaso, et al. "Assessing Lung Cancer Absolute Risk Trajectory Based on a Polygenic Risk Model." Cancer Res 81, no. 6 (Mar 15 2021): 1607-15.
• Integrative Analysis of Lung Cancer, Etiology, Cancer Risk Consortium for Early Detection of Lung, F. Guida, N. Sun, L. E. Bantis, D. C. Muller, P. Li, et al. "Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins." JAMA Oncol 4, no. 10 (Oct 1 2018): e182078.
• Ji, X., Y. Bosse, M. T. Landi, J. Gui, X. Xiao, D. Qian, P. Joubert, et al. "Identification of Susceptibility Pathways for the Role of Chromosome 15q25.1 in Modifying Lung Cancer Risk." Nat Commun 9, no. 1 (Aug 13 2018): 3221.
• Ji, X., S. Mukherjee, M. T. Landi, Y. Bosse, P. Joubert, D. Zhu, I. Gorlov, et al. "Protein-Altering Germline Mutations Implicate Novel Genes Related to Lung Cancer Development." Nat Commun 11, no. 1 (May 11 2020): 2220.
• Jiang, M., A. F. Fares, D. Shepshelovich, P. Yang, D. Christiani, J. Zhang, K. Shiraishi, et al. "The Relationship between Body-Mass Index and Overall Survival in Non-Small Cell Lung Cancer by Sex, Smoking Status, and Race: A Pooled Analysis of 20,937 International Lung Cancer Consortium (Ilcco) Patients." Lung Cancer 152 (Feb 2021): 58-65.
• Jiang, X., H. K. Finucane, F. R. Schumacher, S. L. Schmit, J. P. Tyrer, Y. Han, K. Michailidou, et al. "Shared Heritability and Functional Enrichment across Six Solid Cancers." Nat Commun 10, no. 1 (Jan 25 2019): 431.
• Kachuri, L., J. Helby, S. E. Bojesen, D. C. Christiani, L. Su, X. Wu, A. Tardon, et al. "Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer." Cancer Epidemiol Biomarkers Prev 28, no. 7 (Jul 2019): 1228-37.
• Kachuri, L., M. Johansson, S. R. Rashkin, R. E. Graff, Y. Bosse, V. Manem, N. E. Caporaso, et al. "Immune-Mediated Genetic Pathways Resulting in Pulmonary Function Impairment Increase Lung Cancer Susceptibility." Nat Commun 11, no. 1 (Jan 7 2020): 27.
• Kachuri, L., O. Saarela, S. E. Bojesen, G. Davey Smith, G. Liu, M. T. Landi, N. E. Caporaso, et al. "Mendelian Randomization and Mediation Analysis of Leukocyte Telomere Length and Risk of Lung and Head and Neck Cancers." Int J Epidemiol 48, no. 3 (Jun 1 2019): 751-66.
• Ke, Z., Y. Ma, and X. Lin. "Estimating the Rank of a Spiked Covariance Matrix by Spectral Quantile Matching." J Am Stat Assoc (2021).
• Landy, R., L. C. Cheung, C. D. Berg, A. K. Chaturvedi, H. A. Robbins, and H. A. Katki. "Contemporary Implications of U.S. Preventive Services Task Force and Risk-Based Guidelines for Lung Cancer Screening Eligibility in the United States." Ann Intern Med 171, no. 5 (Sep 3 2019): 384-86.
• Landy, R., C. D. Young, M. Skarzynski, L. C. Cheung, C. D. Berg, M. P. Rivera, H. A. Robbins, A. K. Chaturvedi, and H. A. Katki. "Using Prediction Models to Reduce Persistent Racial and Ethnic Disparities in the Draft 2020 Uspstf Lung Cancer Screening Guidelines." J Natl Cancer Inst 113, no. 11 (Nov 2 2021): 1590-94.
• Lesseur, C., A. Ferreiro-Iglesias, J. D. McKay, Y. Bosse, M. Johansson, V. Gaborieau, M. T. Landi, et al. "Genome-Wide Association Meta-Analysis Identifies Pleiotropic Risk Loci for Aerodigestive Squamous Cell Cancers." PLoS Genet 17, no. 3 (Mar 2021): e1009254.
• Li, D., S. M. Gaynor, C. Quick, J. T. Chen, B. J. K. Stephenson, B. A. Coull, and X. Lin. "Identifying Us County-Level Characteristics Associated with High Covid-19 Burden." BMC Public Health 21, no. 1 (May 28 2021): 1007.
• Li, J. R., M. Tang, Y. Li, C. I. Amos, and C. Cheng. "Genetic Variants Associated Mrna Stability in Lung." BMC Genomics 23, no. 1 (Mar 11 2022): 196.
• Li, X., Z. Li, H. Zhou, S. M. Gaynor, Y. Liu, H. Chen, R. Sun, et al. "Dynamic Incorporation of Multiple in Silico Functional Annotations Empowers Rare Variant Association Analysis of Large Whole-Genome Sequencing Studies at Scale." Nat Genet 52, no. 9 (Sep 2020): 969-83.
• Li, X., G. Yung, H. Zhou, R. Sun, Z. Li, K. Hou, M. J. Zhang, et al. "A Multi-Dimensional Integrative Scoring Framework for Predicting Functional Variants in the Human Genome." Am J Hum Genet 109, no. 3 (Mar 3 2022): 446-56.
• Li, Y., X. Xiao, Y. Bosse, O. Gorlova, I. Gorlov, Y. Han, J. Byun, et al. "Genetic Interaction Analysis among Oncogenesis-Related Genes Revealed Novel Genes and Networks in Lung Cancer Development." Oncotarget 10, no. 19 (Mar 5 2019): 1760-74.
• Li, Y., X. Xiao, Y. Han, O. Gorlova, D. Qian, N. Leighl, J. S. Johansen, et al. "Genome-Wide Interaction Study of Smoking Behavior and Non-Small Cell Lung Cancer Risk in Caucasian Population." Carcinogenesis 39, no. 3 (Mar 8 2018): 336-46.
• Li, Z., X. Li, Y. Liu, J. Shen, H. Chen, H. Zhou, A. C. Morrison, E. Boerwinkle, and X. Lin. "Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies." Am J Hum Genet 104, no. 5 (May 2 2019): 802-14.
• Liu, Y., S. Chen, Z. Li, A. C. Morrison, E. Boerwinkle, and X. Lin. "Acat: A Fast and Powerful P Value Combination Method for Rare-Variant Analysis in Sequencing Studies." Am J Hum Genet 104, no. 3 (Mar 7 2019): 410-21.
• Liu, Y., C. M. Lusk, M. H. Cho, E. K. Silverman, D. Qiao, R. Zhang, M. E. Scheurer, et al. "Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer." J Thorac Oncol 13, no. 10 (Oct 2018): 1483-95.
• Liu, Z., and X. Lin. "A Geometric Perspective on the Power of Principal Component Association Tests in Multiple Phenotype Studies." J Am Stat Assoc 114, no. 527 (2019): 975-90.
• Liu, Z., and X. Lin. "Multiple Phenotype Association Tests Using Summary Statistics in Genome-Wide Association Studies." Biometrics 74, no. 1 (Mar 2018): 165-75.
• Liu, Z., J. Shen, R. Barfield, J. Schwartz, A. A. Baccarelli, and X. Lin. "Large-Scale Hypothesis Testing for Causal Mediation Effects Wwith Applications in Genome-Wide Epigenetic Studies. ." J Am Stat Assoc 19 (2021): 1-5.
• Luyapan, J., X. Ji, S. Li, X. Xiao, D. Zhu, E. J. Duell, D. C. Christiani, et al. "A New Efficient Method to Detect Genetic Interactions for Lung Cancer Gwas." BMC Med Genomics 13, no. 1 (Oct 30 2020): 162.
• McAllister, K., L. E. Mechanic, C. Amos, H. Aschard, I. A. Blair, N. Chatterjee, D. Conti, et al. "Current Challenges and New Opportunities for Gene-Environment Interaction Studies of Complex Diseases." Am J Epidemiol 186, no. 7 (Oct 1 2017): 753-61.
• McCaw, Z. R., S. M. Gaynor, R. Sun, and X. Lin. "Leveraging a Surrogate Outcome to Improve Inference on a Partially Missing Target Outcome." Biometrics (Feb 26 2022).
• McCaw, Z. R., J. M. Lane, R. Saxena, S. Redline, and X. Lin. "Operating Characteristics of the Rank-Based Inverse Normal Transformation for Quantitative Trait Analysis in Genome-Wide Association Studies." Biometrics 76, no. 4 (Dec 2020): 1262-72.
• Naseri, A., J. Shi, X. Lin, S. Zhang, and D. Zhi. "Raffi: Accurate and Fast Familial Relationship Inference in Large Scale Biobank Studies Using Rapid." PLoS Genet 17, no. 1 (Jan 2021): e1009315.
• Ostrin, E. J., D. Sidransky, A. Spira, and S. M. Hanash. "Biomarkers for Lung Cancer Screening and Detection." Cancer Epidemiol Biomarkers Prev 29, no. 12 (Dec 2020): 2411-15.
• Patel, C. J., J. Kerr, D. C. Thomas, B. Mukherjee, B. Ritz, N. Chatterjee, M. Jankowska, et al. "Opportunities and Challenges for Environmental Exposure Assessment in Population-Based Studies." Cancer Epidemiol Biomarkers Prev 26, no. 9 (Sep 2017): 1370-80.
• Pettit, R., B. Peng, P. Yu, P. G. Matos, A. L. Greninger, J. McCashin, and C. I. Amos. "Optimized Post-Vaccination Strategies and Preventative Measures for Sars-Cov-2." medRxiv (Sep 21 2021).
• Pettit, R. W., J. Byun, Y. Han, Q. T. Ostrom, J. Edelson, K. M. Walsh, M. L. Bondy, et al. "The Shared Genetic Architecture between Epidemiological and Behavioral Traits with Lung Cancer." Sci Rep 11, no. 1 (Sep 2 2021): 17559.
• Qian, D. C., D. L. Molfese, J. L. Jin, A. J. Titus, Y. He, Y. Li, M. Vaissie, et al. "Genome-Wide Imaging Association Study Implicates Functional Activity and Glial Homeostasis of the Caudate in Smoking Addiction." BMC Genomics 18, no. 1 (Sep 19 2017): 740.
• Ramsey, A. T., D. Prentice, E. Ballard, L. S. Chen, and L. J. Bierut. "Leverage Points to Improve Smoking Cessation Treatment in a Large Tertiary Care Hospital: A Systems-Based Mixed Methods Study." BMJ Open 9, no. 7 (Jul 2 2019): e030066.
• Ramsey, A. T., E. K. Proctor, D. A. Chambers, J. M. Garbutt, S. Malone, W. G. Powderly, and L. J. Bierut. "Designing for Accelerated Translation (Dart) of Emerging Innovations in Health." J Clin Transl Sci 3, no. 2-3 (Jun 2019): 53-58.
• Robbins, H. A., C. D. Berg, L. C. Cheung, A. K. Chaturvedi, and H. A. Katki. "Identification of Candidates for Longer Lung Cancer Screening Intervals Following a Negative Low-Dose Computed Tomography Result." J Natl Cancer Inst 111, no. 9 (Sep 1 2019): 996-99.
• Robbins, H. A., M. Callister, P. Sasieni, S. L. Quaife, L. C. Cheung, P. Brennan, H. A. Katki, et al. "Benefits and Harms in the National Lung Screening Trial: Expected Outcomes with a Modern Management Protocol." Lancet Respir Med 7, no. 8 (Aug 2019): 655-56.
• Robbins, H. A., L. C. Cheung, A. K. Chaturvedi, D. R. Baldwin, C. D. Berg, and H. A. Katki. "Management of Lung Cancer Screening Results Based on Individual Prediction of Current and Future Lung Cancer Risks." J Thorac Oncol 17, no. 2 (Feb 2022): 252-63.
• Robbins, H. A., and M. Johansson. "Defining Equity in Eligibility for Cancer Screening." JAMA Oncol 6, no. 1 (Jan 1 2020): 156.
• Robbins, H. A., H. A. Katki, L. C. Cheung, R. Landy, and C. D. Berg. "Insights for Management of Ground-Glass Opacities from the National Lung Screening Trial." J Thorac Oncol 14, no. 9 (Sep 2019): 1662-65.
• Rosenberger, A., R. J. Hung, D. C. Christiani, N. E. Caporaso, G. Liu, S. E. Bojesen, L. Le Marchand, et al. "Genetic Modifiers of Radon-Induced Lung Cancer Risk: A Genome-Wide Interaction Study in Former Uranium Miners." Int Arch Occup Environ Health 91, no. 8 (Nov 2018): 937-50.
• Rosenberger, A., N. Muttray, R. J. Hung, D. C. Christiani, N. E. Caporaso, G. Liu, S. E. Bojesen, et al. "Gene-Gene Interaction of Ahrwith and within the Wntcascade Affects Susceptibility to Lung Cancer." Eur J Med Res 27, no. 1 (Jan 31 2022): 14.
• Rosenberger, A., V. Tozzi, H. Bickeboller, and Integral-Ilcco consortium. "Iam Hiq-a Novel Pair of Accuracy Indices for Imputed Genotypes." BMC Bioinformatics 23, no. 1 (Jan 24 2022): 50.
• Shen, S., Y. Wei, Y. Li, W. Duan, X. Dong, L. Lin, D. You, et al. "A Multi-Omics Study Links Tns3 and Sept7 to Long-Term Former Smoking Nsclc Survival." NPJ Precis Oncol 5, no. 1 (May 17 2021): 39.
• Shin, S. J., E. B. Dodd-Eaton, F. Gao, J. Bojadzieva, J. Chen, X. Kong, C. I. Amos, et al. "Penetrance Estimates over Time to First and Second Primary Cancer Diagnosis in Families with Li-Fraumeni Syndrome: A Single Institution Perspective." Cancer Res 80, no. 2 (Jan 15 2020): 347-53.
• Shin, S. J., E. B. Dodd-Eaton, G. Peng, J. Bojadzieva, J. Chen, C. I. Amos, M. N. Frone, et al. "Penetrance of Different Cancer Types in Families with Li-Fraumeni Syndrome: A Validation Study Using Multicenter Cohorts." Cancer Res 80, no. 2 (Jan 15 2020): 354-60.
• Sun, R., R. J. Carroll, D. C. Christiani, and X. Lin. "Testing for Gene-Environment Interaction under Exposure Misspecification." Biometrics 74, no. 2 (Jun 2018): 653-62.
• Sun, R., S. Hui, G. D. Bader, X. Lin, and P. Kraft. "Powerful Gene Set Analysis in Gwas with the Generalized Berk-Jones Statistic." PLoS Genet 15, no. 3 (Mar 2019): e1007530.
• Sun, R., and X. Lin. "Genetic Variant Set-Based Tests Using the Generalized Berk-Jones Statistic with Application to a Genome-Wide Association Study of Breast Cancer." J Am Stat Assoc 115, no. 531 (2020): 1079-91.
• Sun, R., M. Xu, X. Li, S. Gaynor, H. Zhou, Z. Li, Y. Bosse, et al. "Integration of Multiomic Annotation Data to Prioritize and Characterize Inflammation and Immune-Related Risk Variants in Squamous Cell Lung Cancer." Genet Epidemiol 45, no. 1 (Feb 2021): 99-114.
• Thomas, C. E., R. Wang, J. Adams-Haduch, S. E. Murphy, P. M. Ueland, O. Midttun, P. Brennan, et al. "Urinary Cotinine Is as Good a Biomarker as Serum Cotinine for Cigarette Smoking Exposure and Lung Cancer Risk Prediction." Cancer Epidemiol Biomarkers Prev 29, no. 1 (Jan 2020): 127-32.
• Tozzi, V., A. Rosenberger, D. Kube, and H. Bickeboller. "Global, Pathway and Gene Coverage of Three Illumina Arrays with Respect to Inflammatory and Immune-Related Pathways." Eur J Hum Genet 27, no. 11 (Nov 2019): 1716-23.
• Wang, Y., O. Y. Gorlova, I. P. Gorlov, M. Zhu, J. Dai, D. Albanes, S. Lam, et al. "Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls." Cancer Epidemiol Biomarkers Prev 29, no. 7 (Jul 2020): 1423-29.
• Xu, M., Y. Yao, H. Chen, S. Zhang, S. M. Cao, Z. Zhang, B. Luo, et al. "Genome Sequencing Analysis Identifies Epstein-Barr Virus Subtypes Associated with High Risk of Nasopharyngeal Carcinoma." Nat Genet 51, no. 7 (Jul 2019): 1131-36.
• Yarmolinsky, J., V. Diez-Obrero, T. G. Richardson, M. Pigeyre, J. Sjaarda, G. Pare, V. M. Walker, et al. "Genetically Proxied Therapeutic Inhibition of Antihypertensive Drug Targets and Risk of Common Cancers: A Mendelian Randomization Analysis." PLoS Med 19, no. 2 (Feb 2022): e1003897.
• Zhang, Z., X. Xiao, W. Zhou, D. Zhu, and C. I. Amos. "False Positive Findings During Genome-Wide Association Studies with Imputation: Influence of Allele Frequency and Imputation Accuracy." Hum Mol Genet 31, no. 1 (Dec 17 2021): 146-55.
• Zheng, X., C. I. Amos, and H. R. Frost. "Cancer Prognosis Prediction Using Somatic Point Mutation and Copy Number Variation Data: A Comparison of Gene-Level and Pathway-Based Models." BMC Bioinformatics 21, no. 1 (Oct 20 2020): 467.
• Zhou, W., G. Liu, R. J. Hung, P. C. Haycock, M. C. Aldrich, A. S. Andrew, S. M. Arnold, et al. "Causal Relationships between Body Mass Index, Smoking and Lung Cancer: Univariable and Multivariable Mendelian Randomization." Int J Cancer 148, no. 5 (Mar 1 2021): 1077-86.
• Zhu, Y., Y. Wei, R. Zhang, X. Dong, S. Shen, Y. Zhao, J. Bai, et al. "Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis." Cancer Epidemiol Biomarkers Prev 28, no. 5 (May 2019): 935-42.
• S01.07 The U19 Plans for Integration of Biomarkers Into Future Lung Cancer Screening
• MS18.03 Amolecular Diagnostics, Incorporating GWAS and Risk Models: Future Approaches to the Identification of High-Risk Individuals
• Shared heritability and functional enrichment across six solid cancers
• Genome sequencing analysis identifies EpsteinÐBarr virus subtypes associated with high risk of nasopharyngeal carcinoma
• Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
• Cancer prognosis prediction using somatic point mutation and copy number variation data: a comparison of gene-level and pathway-based models
• Assessment of Biomarker Testing for Lung Cancer Screening Eligibility
• Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma
• COVID-19 Community Incidence and Associated Neighborhood-Level Characteristics in Houston, Texas, USA ~

  Publications Produced from this Grant